PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25914645-11 2015 Absolute SLC22A1 IC50 values for efavirenz, darunavir, and prazosin were 21.8, 46.2, and 2.8 muM, respectively. efavirenz 33-42 latexin Homo sapiens 93-96 22252501-4 2012 Efavirenz potently inhibited UGT1A4-mediated trifluoperazine N-glucuronidation and UGT1A9-mediated propofol glucuronidation, with K(i) values of 2.0 and 9.4 muM, respectively. efavirenz 0-9 latexin Homo sapiens 158-161 24091996-5 2013 In contrast, the primary metabolite of efavirenz, 8-hydroxy-efavirenz, stimulated the glycolytic flux in viable astrocytes in a time- and concentration-dependent manner with half-maximal and maximal effects at concentrations of 5 and 10 muM, respectively. efavirenz 39-48 latexin Homo sapiens 237-240 22252501-6 2012 Efavirenz also moderately inhibited UGT1A1-mediated 17beta-estradiol 3-glucuronidation, with a K(i) value of 40.3 muM, but did not inhibit UGT1A6-mediated 1-naphthol glucuronidation. efavirenz 0-9 latexin Homo sapiens 114-117 20408889-6 2010 RESULTS: Efavirenz induced growth in MCF-7 cells with an estimated effective concentration for half-maximal growth (EC(50)) of 15.7 muM. efavirenz 9-18 latexin Homo sapiens 132-135 20408889-8 2010 Further, efavirenz binds directly to the ER [inhibitory concentration for half maximal binding (IC(50)) of ~52 muM] at a roughly 1000-fold higher concentration than observed with 17beta-oestradiol. efavirenz 9-18 latexin Homo sapiens 111-114