PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22297387-7 2012 Efavirenz (single dose) slightly increased ezetimibe absorption and markedly decreased exposure to ezetimibe-glucuronide (single dose and multiple dose), which may be explained by inhibition of UGT1A1 and ABCB1 (in vitro data). efavirenz 0-9 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 194-200 34093191-3 2021 UGT1A1*28 and CYP2B6 c.516G>T have been proposed to be related with higher toxicity by ATV and EFV, respectively. efavirenz 95-98 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 0-6 32829410-5 2021 Associations were characterized with CYP2B6 and UGT1A1 genotypes that affect efavirenz and INSTI metabolism, respectively. efavirenz 77-86 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 48-54 22252501-6 2012 Efavirenz also moderately inhibited UGT1A1-mediated 17beta-estradiol 3-glucuronidation, with a K(i) value of 40.3 muM, but did not inhibit UGT1A6-mediated 1-naphthol glucuronidation. efavirenz 0-9 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 36-42