PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17082249-1	2007	BACKGROUND: CYP2B6 is a highly variable and polymorphic cytochrome P450 (CYP) enzyme involved in the biotransformation of an increasing number of drugs, including cyclophosphamide, bupropion, and the nonnucleosidic reverse transcriptase inhibitor efavirenz.	efavirenz	247-256	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	56-71	
17082249-1	2007	BACKGROUND: CYP2B6 is a highly variable and polymorphic cytochrome P450 (CYP) enzyme involved in the biotransformation of an increasing number of drugs, including cyclophosphamide, bupropion, and the nonnucleosidic reverse transcriptase inhibitor efavirenz.	efavirenz	247-256	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	12-15	
15769884-1	2005	The polymorphic human cytochrome P450 (P450) 2B6 is primarily responsible for the metabolism of several clinically relevant drugs including bupropion, cyclophosphamide, propofol, and efavirenz.	efavirenz	183-192	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	22-48	
35107462-6	2022	Finally, the metabolite identification opportunities were also explored using efavirenz as an example drug with complex primary and secondary metabolism involving a combination of CYP, UGT and sulfotransferase enzymes.	efavirenz	78-87	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	180-183	
35194103-1	2022	Human CYP2B6 enzyme although constitutes relatively low proportion (1-4%) of hepatic cytochrome P450 content, it is the major catalyst of metabolism of several clinically important drugs (efavirenz, cyclophosphamide, bupropion, methadone).	efavirenz	188-197	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	85-100	
31628422-2	2020	Cytochrome P450 (CYP) CYP2B6 G516T (rs3745274) is a well-known predictor of efavirenz disposition.	efavirenz	76-85	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	0-15	
31628422-2	2020	Cytochrome P450 (CYP) CYP2B6 G516T (rs3745274) is a well-known predictor of efavirenz disposition.	efavirenz	76-85	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	17-20	
24316028-1	2014	Efavirenz (EFV) exhibits interindividual pharmacokinetic variability caused by differences in cytochrome P450 (CYP) expression.	efavirenz	0-9	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	94-109	
24316028-1	2014	Efavirenz (EFV) exhibits interindividual pharmacokinetic variability caused by differences in cytochrome P450 (CYP) expression.	efavirenz	0-9	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	111-114