PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20002083-4 2009 WHAT THIS STUDY ADDS: * In the present work, we studied the effect of EFV on the activity of PON-1 and showed, for the first time, that EFV-based antiretroviral therapy is associated with a better antioxidant function, i.e. with a higher PON-1 activity. efavirenz 70-73 paraoxonase 1 Homo sapiens 93-98 20002083-4 2009 WHAT THIS STUDY ADDS: * In the present work, we studied the effect of EFV on the activity of PON-1 and showed, for the first time, that EFV-based antiretroviral therapy is associated with a better antioxidant function, i.e. with a higher PON-1 activity. efavirenz 136-139 paraoxonase 1 Homo sapiens 93-98 20002083-4 2009 WHAT THIS STUDY ADDS: * In the present work, we studied the effect of EFV on the activity of PON-1 and showed, for the first time, that EFV-based antiretroviral therapy is associated with a better antioxidant function, i.e. with a higher PON-1 activity. efavirenz 136-139 paraoxonase 1 Homo sapiens 238-243 20002083-10 2009 The influence of treatment with EFV, HDL-c and CD4 cell count on PON-1 activity was analysed. efavirenz 32-35 paraoxonase 1 Homo sapiens 65-70 20002083-13 2009 CONCLUSIONS: EFV-based antiretroviral regimens are associated with HDL particles with a better antioxidant function, i.e. with a higher PON-1 activity. efavirenz 13-16 paraoxonase 1 Homo sapiens 136-141