PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31939088-10	2020	Mice treated with GW0742 showed significantly less severe behavioral deficits compared to the control group, accompanied by increased expression of PPAR-beta/delta and Bcl-2, and increased expression of IL-1beta, TNF-alpha, and Bax decreased simultaneously in the GW0742-treated group.	GW0742	18-24	tumor necrosis factor	Mus musculus	213-222	
21765606-3	2011	Mice treated with copper and peroxisome proliferator-activated receptor beta/delta agonist GW0742 had significantly less body weight loss, less serum alanine aminotransferase increase, less tumor necrosis factor alpha, macrophage inflammatory protein-2 and 8-hydroxy-2"-deoxyguanosine upregulation than copper treated mice.	GW0742	91-97	tumor necrosis factor	Mus musculus	190-217	
20709805-7	2010	Furthermore, in lipopolysaccharide-stimulated J774.A1 macrophages, GW0742 reduced TNFalpha production by inhibiting NF-kappaB activation.	GW0742	67-73	tumor necrosis factor	Mus musculus	82-90	
20709805-8	2010	RNA silencing of PPARdelta abrogated the inhibitory effects of GW0742 on TNFalpha production.	GW0742	63-69	tumor necrosis factor	Mus musculus	73-81	
18622026-5	2008	GW0742 treatment resulted in reduced serum ALT concentration and lower expression of CCl(4)-induced TNF-alpha, S100A6, monocyte chemoattractant protein-1 (MCP1), and TWEAKr in wild-type mice, and these effects were not observed in PPARbeta/delta-null mice.	GW0742	0-6	tumor necrosis factor	Mus musculus	100-109	
18622687-6	2008	Protein and mRNA levels of the pro-inflammatory cytokines IL-6, IL-1beta and TNFalpha in BALF were found to be significantly decreased in GW0742-treated animals (30 mg/kg).	GW0742	138-144	tumor necrosis factor	Mus musculus	77-85	
33790957-6	2021	The selective PPARbeta/delta agonist GW0742 significantly decreased inflammation-related mRNA expression in hDPCs (IL6, IL1beta, TNFalpha, MMP1, and MMP2) and RAW264.7 cells (Il6 and Tnfalpha).	GW0742	37-43	tumor necrosis factor	Mus musculus	129-137	
33790957-6	2021	The selective PPARbeta/delta agonist GW0742 significantly decreased inflammation-related mRNA expression in hDPCs (IL6, IL1beta, TNFalpha, MMP1, and MMP2) and RAW264.7 cells (Il6 and Tnfalpha).	GW0742	37-43	tumor necrosis factor	Mus musculus	183-191