PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24774438-8 2014 RESULTS: The pretreatment with GW0742 significantly increased the expression of Bcl-2, and significantly decreased in the volume of infarction, NDS, edema, expressions of IL-1beta, NF-kappaB, TNFalpha, and Bax, contents of iNOS and the apoptotic cells in infarct cerebral hemisphere compared with rats in the vehicle group at 24 hours after MCAO. GW0742 31-37 interleukin 1 beta Rattus norvegicus 171-179 21825230-6 2011 Moreover, GW0742 inhibited vascular superoxide production, downregulated p22(phox) and p47(phox) proteins, decreased both basal and angiotensin II-stimulated NADPH oxidase activity, inhibited extracellular-regulated kinase 1/2 activation, and reduced the expression of the proinflammatory and proatherogenic genes, interleukin 1beta, interleukin 6, or intercellular adhesion molecule 1. GW0742 10-16 interleukin 1 beta Rattus norvegicus 315-332 18293166-7 2008 Meanwhile, GW0742 pretreatment exerted inhibition on mRNA expression augmentation of such cytokines as MMP9, MMP2, and IL-1beta in hypertrophic myocytes. GW0742 11-17 interleukin 1 beta Rattus norvegicus 119-127