PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29578577-2 2018 Posaconazole (POS), a substrate of glucuronosyltransferase and P-glycoprotein, and voriconazole (VRC), a substrate of CYP2C9/19, are commonly administered to transplant recipients. posaconazole 0-12 ATP binding cassette subfamily B member 1 Homo sapiens 63-77 31741622-1 2019 The aim of this study was to determine the impact of ABCB1 polymorphism, BMI, age and drug co-administration on safety and efficiency of posaconazole (PCZ) oral suspension treatment in children with hematological diseases. posaconazole 137-149 ATP binding cassette subfamily B member 1 Homo sapiens 53-58 31741622-1 2019 The aim of this study was to determine the impact of ABCB1 polymorphism, BMI, age and drug co-administration on safety and efficiency of posaconazole (PCZ) oral suspension treatment in children with hematological diseases. posaconazole 151-154 ATP binding cassette subfamily B member 1 Homo sapiens 53-58 30259783-0 2019 Posaconazole-digoxin drug-drug interaction mediated by inhibition of P-glycoprotein. posaconazole 0-12 ATP binding cassette subfamily B member 1 Homo sapiens 69-83 30259783-2 2019 Posaconazole is not extensively metabolized by these isozymes but is both a p-glycoprotein (P-gp) substrate and inhibitor. posaconazole 0-12 ATP binding cassette subfamily B member 1 Homo sapiens 76-90 30259783-2 2019 Posaconazole is not extensively metabolized by these isozymes but is both a p-glycoprotein (P-gp) substrate and inhibitor. posaconazole 0-12 ATP binding cassette subfamily B member 1 Homo sapiens 92-96 32472569-3 2021 PCZ is an inhibitor of cytochrome P450 3A4 and P-glycoprotein. posaconazole 0-3 ATP binding cassette subfamily B member 1 Homo sapiens 47-61 29578577-2 2018 Posaconazole (POS), a substrate of glucuronosyltransferase and P-glycoprotein, and voriconazole (VRC), a substrate of CYP2C9/19, are commonly administered to transplant recipients. posaconazole 14-17 ATP binding cassette subfamily B member 1 Homo sapiens 63-77 27530244-5 2017 We speculate that posaconazole may inhibit the cytarabine efflux through P-glycoprotein inhibition leading to the patient"s palmar-plantar erythrodysesthesia and subsequent aplasia. posaconazole 18-30 ATP binding cassette subfamily B member 1 Homo sapiens 73-87 27510521-10 2016 CONCLUSIONS: Voriconazole, and to a minor extent posaconazole, increase plasma exposure to sublingual buprenorphine, probably via inhibition of cytochrome P450 3 A and/or P-glycoprotein. posaconazole 49-61 ATP binding cassette subfamily B member 1 Homo sapiens 171-185 27001813-4 2016 Fifty percent inhibitory concentrations (IC50s) for P-gp and BCRP were both 2 muM for itraconazole, 5 and 12 muM for hydroxyitraconazole, 3 and 6 muM for posaconazole, and 3 and 11 muM for isavuconazole, respectively. posaconazole 154-166 ATP binding cassette subfamily B member 1 Homo sapiens 52-56 21420575-8 2011 Moreover, itraconazole and posaconazole are substrates and inhibitors of the transporter protein, P-glycoprotein. posaconazole 27-39 ATP binding cassette subfamily B member 1 Homo sapiens 98-112