PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33645069-15	2021	The gene and protein expressions of PTEN in icaritin groups were elevated(P<0.05).	icaritin	44-52	phosphatase and tensin homolog	Homo sapiens	36-40	
32256768-9	2020	Furthermore, icaritin treatment increased the expression of estrogen receptor (ER)beta and the phosphatase and tensin (PTEN) homolog oncoprotein, thus reducing the expression of downstream targets of PTEN; protein kinase B (Akt) and phosphorylated Akt.	icaritin	13-21	phosphatase and tensin homolog	Homo sapiens	95-117	
32256768-9	2020	Furthermore, icaritin treatment increased the expression of estrogen receptor (ER)beta and the phosphatase and tensin (PTEN) homolog oncoprotein, thus reducing the expression of downstream targets of PTEN; protein kinase B (Akt) and phosphorylated Akt.	icaritin	13-21	phosphatase and tensin homolog	Homo sapiens	119-123	
32256768-9	2020	Furthermore, icaritin treatment increased the expression of estrogen receptor (ER)beta and the phosphatase and tensin (PTEN) homolog oncoprotein, thus reducing the expression of downstream targets of PTEN; protein kinase B (Akt) and phosphorylated Akt.	icaritin	13-21	phosphatase and tensin homolog	Homo sapiens	200-204	
26356761-0	2015	Icaritin inhibits the invasion and epithelial-to-mesenchymal transition of glioblastoma cells by targeting EMMPRIN via PTEN/AKt/HIF-1alpha signalling.	icaritin	0-8	phosphatase and tensin homolog	Homo sapiens	119-123	
26356761-5	2015	Furthermore, the findings strongly indicate that the modulatory effect of icaritin on EMMPRIN is mediated via the PTEN/Akt/HIF-1alpha signalling pathway.	icaritin	74-82	phosphatase and tensin homolog	Homo sapiens	114-118	
31829310-0	2019	Down-regulation of microRNA-10a mediates the anti-tumor effect of icaritin in A549 cells via the PTEN/AKT and ERK pathway.	icaritin	66-74	phosphatase and tensin homolog	Homo sapiens	97-101	
31829310-7	2019	Furthermore, we found that the regulation of miR-10a in the anti-tumor effects of icaritin was mediated via the PTEN/AKT/ERK pathway by directly targeting to PTEN.	icaritin	82-90	phosphatase and tensin homolog	Homo sapiens	112-116	
31829310-7	2019	Furthermore, we found that the regulation of miR-10a in the anti-tumor effects of icaritin was mediated via the PTEN/AKT/ERK pathway by directly targeting to PTEN.	icaritin	82-90	phosphatase and tensin homolog	Homo sapiens	158-162	
31829310-8	2019	Taken together, miR-10a targets PTEN to mediate the anti-tumor effect of icaritin in A549 cells, which provides a novel insight into the anti-tumor mechanism of icaritin and may provide a new strategy for lung cancer therapy.	icaritin	73-81	phosphatase and tensin homolog	Homo sapiens	32-36	
31829310-8	2019	Taken together, miR-10a targets PTEN to mediate the anti-tumor effect of icaritin in A549 cells, which provides a novel insight into the anti-tumor mechanism of icaritin and may provide a new strategy for lung cancer therapy.	icaritin	161-169	phosphatase and tensin homolog	Homo sapiens	32-36