PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23566810-7 2013 The results showed that icaritin significantly inhibited the NO, IL-6, IL-10 TNF-alpha, and MCP-1 production both in vitro and in vivo. icaritin 24-32 interleukin 6 Mus musculus 65-69 27207661-0 2016 Icaritin suppresses development of neuroendocrine differentiation of prostate cancer through inhibition of IL-6/STAT3 and Aurora kinase A pathways in TRAMP mice. icaritin 0-8 interleukin 6 Mus musculus 107-111 25865044-0 2015 Icaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3. icaritin 0-8 interleukin 6 Mus musculus 52-56 25865044-6 2015 We also demonstrated that in MM xenograft mouse models, icaritin suppressed tumor growth and decreased serum IL-6 and IgE levels, but did not show adverse reactions such as body weight loss. icaritin 56-64 interleukin 6 Mus musculus 109-113 25865044-7 2015 The anti-MM activity of icaritin was mainly mediated by inhibiting IL-6/JAK2/STAT3 signaling. icaritin 24-32 interleukin 6 Mus musculus 67-71 24064280-10 2013 Our data also suggests that icaritin administration remarkably attenuated the increases in serum IL-6 and TNF-alpha level that occur following exposure to social defeat. icaritin 28-36 interleukin 6 Mus musculus 97-101