PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31985018-5	2020	Treatment with 1 microM Icaritin upregulated osteocalcin, RUNX family transcription factor 2, tissue-nonspecific alkaline phosphatase and beta-catenin, and suppressed sclerostin (SOST) gene expression in different stages of osteogenic differentiation.	icaritin	24-32	bone gamma-carboxyglutamate protein	Homo sapiens	45-56	
28260001-4	2017	Data showed that icaritin at concentrations 10-7-10-5 M significantly increased alkaline phosphatase activity, OC secretion at different time points, and calcium deposition at day 21.	icaritin	17-25	bone gamma-carboxyglutamate protein	Homo sapiens	111-113	
28260001-5	2017	In addition, icaritin upregulated the mRNA expression of genes for bone morphogenetic proteins (BMP-2, -4 and -7), bone transcription factors (Runx2 and Dlx5) and bone matrix proteins (ALP, OC and Col-1).	icaritin	13-21	bone gamma-carboxyglutamate protein	Homo sapiens	190-192	
28260001-6	2017	Moreover, icaritin increased the protein levels of BMPs, Runx2 and OC, as detected by western blot analysis.	icaritin	10-18	bone gamma-carboxyglutamate protein	Homo sapiens	67-69