PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24064280-0 2013 Icaritin opposes the development of social aversion after defeat stress via increases of GR mRNA and BDNF mRNA in mice. icaritin 0-8 brain derived neurotrophic factor Mus musculus 101-105 32476534-0 2020 Antagonizing effect of icaritin on apoptosis and injury of hippocampal neurocytes induced by amyloid beta via GR/BDNF signaling pathway. icaritin 23-31 brain derived neurotrophic factor Mus musculus 113-117 32476534-6 2020 ICA at 20 micromol/L (ICA20) the most significantly increased the viability of HT22 cells and the expressions of GR and BDNF in HT22 cells. icaritin 0-3 brain derived neurotrophic factor Mus musculus 120-124 32476534-8 2020 More importantly, shRNA-GR reversed the positive effects of ICA20 on AD.Conclusions: ICA protected hippocampal neurocytes against Abeta25-35 via GR/BDNF signaling pathway. icaritin 60-63 brain derived neurotrophic factor Mus musculus 148-152