PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28993452-4 2017 We found that clarithromycin concentration dependently lowered CYP11B2 gene expression (by 60%) and aldosterone secretion (by 70%; P<0.001 for both) in CD56+ cells isolated ex vivo from KCNJ5 mutated APAs, although it was ineffective in CD56+ cells from wild-type APAs. Clarithromycin 14-28 cytochrome P450 family 11 subfamily B member 2 Homo sapiens 63-70 34440230-9 2021 The mutant-transfected HAC15 cells increased the expression of CYP11B2 and aldosterone secretion, which was partially suppressed by clarithromycin and nifedipine but not roxithromycin treatment. Clarithromycin 132-146 cytochrome P450 family 11 subfamily B member 2 Homo sapiens 63-70