PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30186615-10	2018	However, these alterations were not observed after pretreatment with high-dose (10 muM) CAM, which suppressed phosphorylation of cell proliferation-associated ERK to cause a significant (p < 0.01) decrease in cell viability.	Clarithromycin	88-91	mitogen-activated protein kinase 1	Homo sapiens	159-162	
30186615-12	2018	On the other hand, pretreatment with high-dose CAM suppressed phosphorylation of cell proliferation-associated ERK and decreased cell viability.	Clarithromycin	47-50	mitogen-activated protein kinase 1	Homo sapiens	111-114	
17412724-0	2007	Clarithromycin has an immunomodulatory effect on ERK-mediated inflammation induced by Pseudomonas aeruginosa flagellin.	Clarithromycin	0-14	mitogen-activated protein kinase 1	Homo sapiens	49-52	
17412724-2	2007	Clarithromycin initially decreases, then increases and finally produces a sustained suppression of interleukin (IL)-8 secretion from normal human bronchial epithelial (NHBE) cells through inhibition and activation of extracellular signal-regulated kinase (ERK).	Clarithromycin	0-14	mitogen-activated protein kinase 1	Homo sapiens	217-254	
17412724-2	2007	Clarithromycin initially decreases, then increases and finally produces a sustained suppression of interleukin (IL)-8 secretion from normal human bronchial epithelial (NHBE) cells through inhibition and activation of extracellular signal-regulated kinase (ERK).	Clarithromycin	0-14	mitogen-activated protein kinase 1	Homo sapiens	256-259	
17412724-8	2007	Clarithromycin significantly decreased flagellin-induced IL-8 over the first 9 h but not at 24 h. A 60 min exposure to clarithromycin decreased flagellin-induced ERK phosphorylation, but at 24 h, clarithromycin increased phospho-ERK1/2 beyond the effect of flagellin alone.	Clarithromycin	0-14	mitogen-activated protein kinase 1	Homo sapiens	162-165	
17412724-8	2007	Clarithromycin significantly decreased flagellin-induced IL-8 over the first 9 h but not at 24 h. A 60 min exposure to clarithromycin decreased flagellin-induced ERK phosphorylation, but at 24 h, clarithromycin increased phospho-ERK1/2 beyond the effect of flagellin alone.	Clarithromycin	119-133	mitogen-activated protein kinase 1	Homo sapiens	162-165	
16641444-4	2006	Therefore, we studied normal human bronchial epithelial (NHBE) cells to determine whether clarithromycin (CAM) suppresses ERK, delays bronchial epithelial cells from progressing to S phase, and delays cell growth.	Clarithromycin	90-104	mitogen-activated protein kinase 1	Homo sapiens	122-125	
16641444-4	2006	Therefore, we studied normal human bronchial epithelial (NHBE) cells to determine whether clarithromycin (CAM) suppresses ERK, delays bronchial epithelial cells from progressing to S phase, and delays cell growth.	Clarithromycin	106-109	mitogen-activated protein kinase 1	Homo sapiens	122-125