PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16641444-4 2006 Therefore, we studied normal human bronchial epithelial (NHBE) cells to determine whether clarithromycin (CAM) suppresses ERK, delays bronchial epithelial cells from progressing to S phase, and delays cell growth. Clarithromycin 90-104 mitogen-activated protein kinase 1 Homo sapiens 122-125 30186615-10 2018 However, these alterations were not observed after pretreatment with high-dose (10 muM) CAM, which suppressed phosphorylation of cell proliferation-associated ERK to cause a significant (p < 0.01) decrease in cell viability. Clarithromycin 88-91 mitogen-activated protein kinase 1 Homo sapiens 159-162 30186615-12 2018 On the other hand, pretreatment with high-dose CAM suppressed phosphorylation of cell proliferation-associated ERK and decreased cell viability. Clarithromycin 47-50 mitogen-activated protein kinase 1 Homo sapiens 111-114 17412724-0 2007 Clarithromycin has an immunomodulatory effect on ERK-mediated inflammation induced by Pseudomonas aeruginosa flagellin. Clarithromycin 0-14 mitogen-activated protein kinase 1 Homo sapiens 49-52 17412724-2 2007 Clarithromycin initially decreases, then increases and finally produces a sustained suppression of interleukin (IL)-8 secretion from normal human bronchial epithelial (NHBE) cells through inhibition and activation of extracellular signal-regulated kinase (ERK). Clarithromycin 0-14 mitogen-activated protein kinase 1 Homo sapiens 217-254 17412724-2 2007 Clarithromycin initially decreases, then increases and finally produces a sustained suppression of interleukin (IL)-8 secretion from normal human bronchial epithelial (NHBE) cells through inhibition and activation of extracellular signal-regulated kinase (ERK). Clarithromycin 0-14 mitogen-activated protein kinase 1 Homo sapiens 256-259 17412724-8 2007 Clarithromycin significantly decreased flagellin-induced IL-8 over the first 9 h but not at 24 h. A 60 min exposure to clarithromycin decreased flagellin-induced ERK phosphorylation, but at 24 h, clarithromycin increased phospho-ERK1/2 beyond the effect of flagellin alone. Clarithromycin 0-14 mitogen-activated protein kinase 1 Homo sapiens 162-165 17412724-8 2007 Clarithromycin significantly decreased flagellin-induced IL-8 over the first 9 h but not at 24 h. A 60 min exposure to clarithromycin decreased flagellin-induced ERK phosphorylation, but at 24 h, clarithromycin increased phospho-ERK1/2 beyond the effect of flagellin alone. Clarithromycin 119-133 mitogen-activated protein kinase 1 Homo sapiens 162-165 16641444-4 2006 Therefore, we studied normal human bronchial epithelial (NHBE) cells to determine whether clarithromycin (CAM) suppresses ERK, delays bronchial epithelial cells from progressing to S phase, and delays cell growth. Clarithromycin 106-109 mitogen-activated protein kinase 1 Homo sapiens 122-125