PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25500904-12	2014	We show for the first time that AZM and to a lesser extent CLM act as immunosuppressive agents on CD4(+) T-cells by inhibiting mTOR activity.	Clarithromycin	59-62	CD4 molecule	Homo sapiens	98-101	
15336223-5	2004	Prophylaxis with azithromycin or clarithromycin is recommended for all patients with CD4 counts less than 50 cells/mL.	Clarithromycin	33-47	CD4 molecule	Homo sapiens	85-88	
16159721-12	2005	Systemic clarithromycin treatment decreased the conjunctival flora of HIV patients, including those who had a CD4 count that was less than 50/microl.	Clarithromycin	9-23	CD4 molecule	Homo sapiens	110-113	
11742432-1	2001	Clarithromycin 500 mg po bid or azithromycin 1200 mg po weekly is recommended as first line prophylaxis for Mycobacterium avium complex (MAC) in patients with HIV infection whose CD4 counts are <50 cells/microL.	Clarithromycin	0-14	CD4 molecule	Homo sapiens	179-182	
9292586-7	1997	RESULTS: For patients with AIDS and those having CD4 counts <75 cells/mm3, azithromycin, clarithromycin, and rifabutin prophylaxis increased lifetime per person MAC-related costs by $994, $2,117, and $2,185 U.S., respectively.	Clarithromycin	92-106	CD4 molecule	Homo sapiens	49-52	
35440370-5	2022	RESULTS: Co-incubation of clarithromycin with spike protein-stimulated healthy volunteer PBMCs ex vivo resulted in an increase in CD8+ (p = 0.004) and CD4+ (p = 0.007) IL-2, with a decrease in CD8+ (p = 0.032) and CD4+ (p = 0.007) IL-10.	Clarithromycin	26-40	CD4 molecule	Homo sapiens	151-154	
8764523-4	1996	The incidence of CE in patients with CD4 counts < 50/mm3 treated with clarithromycin prophylaxis for MAC was compared with patients not receiving clarithromycin prophylaxis.	Clarithromycin	73-87	CD4 molecule	Homo sapiens	37-40	
35440370-6	2022	The addition of amoxicillin to clarithromycin resulted in an increase in CD8+ IL-6 (p = 0.010), decrease in CD8+ (p = 0.014) and CD4+ (p = 0.022) TNF-alpha, and decrease in CD8+ IFN-alpha (p = 0.038).	Clarithromycin	31-45	CD4 molecule	Homo sapiens	129-132	
35440370-5	2022	RESULTS: Co-incubation of clarithromycin with spike protein-stimulated healthy volunteer PBMCs ex vivo resulted in an increase in CD8+ (p = 0.004) and CD4+ (p = 0.007) IL-2, with a decrease in CD8+ (p = 0.032) and CD4+ (p = 0.007) IL-10.	Clarithromycin	26-40	CD4 molecule	Homo sapiens	214-217