PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31129789-0	2019	Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole.	Clarithromycin	203-217	solute carrier organic anion transporter family member 1B1	Homo sapiens	82-89	
32628085-3	2020	Some of the exposure-enhancing effects of clarithromycin may originate from its inhibitory potential toward OATP1B1, because the estimated effects of itraconazole (also a P450 3A4 inhibitor) were only minor.Simulations using the current PBPK model in groups of virtual subjects with or without renal or hepatic impairment revealed modified pharmacokinetic profiles for pemafibrate following co-administration of typical P450 inhibitors.	Clarithromycin	42-56	solute carrier organic anion transporter family member 1B1	Homo sapiens	108-115	
31129789-0	2019	Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole.	Clarithromycin	203-217	solute carrier organic anion transporter family member 1B1	Homo sapiens	91-98	
27822600-1	2017	Clarithromycin is a substrate and mechanism-based inhibitor of cytochrome P450 (CYP) 3A4 as well as a substrate and competitive inhibitor of P-glycoprotein (P-gp) and organic anion-transporting polypeptides (OATP) 1B1 and 1B3.	Clarithromycin	0-14	solute carrier organic anion transporter family member 1B1	Homo sapiens	167-225	
25534598-1	2015	BACKGROUND: The cytochrome P450 3A4 (CYP3A4) inhibitor clarithromycin may also inhibit liver-specific organic anion-transporting polypeptides (OATP1B1 and OATP1B3).	Clarithromycin	55-69	solute carrier organic anion transporter family member 1B1	Homo sapiens	143-150	
25106415-4	2014	As for ketoconazole, uptake of clarithromycin, itraconazole, and hydroxyitraconazole into OATP1B1, OATP1B3, OATP2B1, and OCT1 expressing human embryonic kidney 293 (HEK293) cells was not greater than in vector controls.	Clarithromycin	31-45	solute carrier organic anion transporter family member 1B1	Homo sapiens	90-97