PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8931931-4 1996 From these results, we observed that a primary bromide produces a greater inhibition of 17 beta-HSD activity than secondary bromide, and that a shorter 16 alpha-side chain increases the inhibiting activity. Bromides 47-54 hydroxysteroid 17-beta dehydrogenase 1 Homo sapiens 88-99 7846736-7 1994 Thus, the introduction of a side-chain with a secondary bromide and a butyl methyl amide group at the 16 alpha-position of estradiol has two interesting effects; namely an inhibition of cytosolic 17 beta-HSD and a blockade of the estrogenic effect of estradiol. Bromides 56-63 hydroxysteroid 17-beta dehydrogenase 1 Homo sapiens 196-207