PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23441447-7 2013 Twenty-four hours of treatment with GA (0.5 micromol/L) following transfection with PKM2 siRNA-1 inhibited the vitality of the PC3 cells by 68%, increased their apoptosis, and significantly down-regulated the mRNA and protein levels of c-myc (50% and 35%) and cyclin D1 (60% and 20%) (P < 0.05). gambogic acid 36-38 cyclin D1 Homo sapiens 260-269 21331449-7 2011 GA mediated the G0/G1 phase arrest in U2OS cells; this arrest was associated with a decrease in phospho-GSK3-beta (Ser9) and the expression of cyclin D1. gambogic acid 0-2 cyclin D1 Homo sapiens 143-152