PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29345888-1 2016 It has been reported that gambogic acid (GA), the main active component of gamboge, could directly inhibit and reduce the expression level of P-gp by promoting protein degradation through post-translational proteasome pathway. gambogic acid 41-43 phosphoglycolate phosphatase Homo sapiens 142-146 29345888-1 2016 It has been reported that gambogic acid (GA), the main active component of gamboge, could directly inhibit and reduce the expression level of P-gp by promoting protein degradation through post-translational proteasome pathway. gambogic acid 26-39 phosphoglycolate phosphatase Homo sapiens 142-146 22759348-4 2013 GA dose dependently inhibited ABCB1 activity levels in the in vitro Pgp-Glo assay system and increased the cellular accumulation of ABCB1 substrate adriamycin. gambogic acid 0-2 phosphoglycolate phosphatase Homo sapiens 68-71 22541076-12 2012 It is concluded that GA can enhance the sensitivity of K562/A02 cells to ADM, which may be related to increasing cell apoptosis and down-regulating expressions of Survivin and P-gp. gambogic acid 21-23 phosphoglycolate phosphatase Homo sapiens 176-180