PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26750665-9 2016 Furthermore, the ERK and p38 MAPK pathways were involved in the GA-mediated down-regulation of CES1 and CES2. gambogic acid 64-66 carboxylesterase 2 Homo sapiens 104-108 26750665-7 2016 Moreover, the GA-mediated repression of CES2 attenuated CPT-11-induced apoptosis. gambogic acid 14-16 carboxylesterase 2 Homo sapiens 40-44 26750665-11 2016 Taken together, our data suggest that GA is a potent repressor of CES1 and CES2 and that combination with GA will affect the metabolism of drugs containing ester bonds. gambogic acid 38-40 carboxylesterase 2 Homo sapiens 75-79