PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31513784-0	2019	Involvement of E-cadherin/AMPK/mTOR axis in LKB1-induced sensitivity of non-small cell lung cancer to gambogic acid.	gambogic acid	102-115	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	26-30	
31513784-6	2019	Further studies reveal that GA increases p-AMPK levels through up-regulation of E-cadherin associated with LKB1.	gambogic acid	28-30	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	43-47	
23665322-6	2013	Further, we provided evidence to support that AMPK (AMP-activated protein kinase) activation mediated gambogic acid-induced LRIG1 upregulation, U87 cell apoptosis and growth inhibition, while AMPK inhibition by shRNA or compound C reduced gambogic acid-induced EGFR/Akt inhibition and cytotoxicity in U87 cells.	gambogic acid	239-252	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	46-50	
23665322-0	2013	Gambogic acid induces EGFR degradation and Akt/mTORC1 inhibition through AMPK dependent-LRIG1 upregulation in cultured U87 glioma cells.	gambogic acid	0-13	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	73-77	
23665322-6	2013	Further, we provided evidence to support that AMPK (AMP-activated protein kinase) activation mediated gambogic acid-induced LRIG1 upregulation, U87 cell apoptosis and growth inhibition, while AMPK inhibition by shRNA or compound C reduced gambogic acid-induced EGFR/Akt inhibition and cytotoxicity in U87 cells.	gambogic acid	102-115	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	46-50	
23665322-6	2013	Further, we provided evidence to support that AMPK (AMP-activated protein kinase) activation mediated gambogic acid-induced LRIG1 upregulation, U87 cell apoptosis and growth inhibition, while AMPK inhibition by shRNA or compound C reduced gambogic acid-induced EGFR/Akt inhibition and cytotoxicity in U87 cells.	gambogic acid	102-115	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	52-80	
23665322-6	2013	Further, we provided evidence to support that AMPK (AMP-activated protein kinase) activation mediated gambogic acid-induced LRIG1 upregulation, U87 cell apoptosis and growth inhibition, while AMPK inhibition by shRNA or compound C reduced gambogic acid-induced EGFR/Akt inhibition and cytotoxicity in U87 cells.	gambogic acid	102-115	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	192-196	
23665322-6	2013	Further, we provided evidence to support that AMPK (AMP-activated protein kinase) activation mediated gambogic acid-induced LRIG1 upregulation, U87 cell apoptosis and growth inhibition, while AMPK inhibition by shRNA or compound C reduced gambogic acid-induced EGFR/Akt inhibition and cytotoxicity in U87 cells.	gambogic acid	239-252	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	52-80