PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34181351-0	2021	Gambogic Acid Inhibits Wnt/beta-catenin Signaling and Induces ER Stress-Mediated Apoptosis in Human Cholangiocarcinoma.	gambogic acid	0-13	catenin beta 1	Homo sapiens	27-39	
34181351-3	2021	This study was aimed to investigate GA"s effect on human CCA cell lines, KKU-M213 and HuCCA-1, and its associated mechanisms on Wnt/beta-catenin signaling pathway.	gambogic acid	36-38	catenin beta 1	Homo sapiens	132-144	
34181351-5	2021	The effect of GA mediated Wnt/beta-catenin and ER stress were determined by luciferase-reporter assay, qRT-PCR, and western blot analysis.	gambogic acid	14-16	catenin beta 1	Homo sapiens	30-42	
34181351-7	2021	GA attenuated beta-catenin transcriptional levels, decreased beta-catenin protein, and suppressed the expression of c-Myc, a downstream target gene of Wnt/beta-catenin signaling.	gambogic acid	0-2	catenin beta 1	Homo sapiens	14-26	
34181351-7	2021	GA attenuated beta-catenin transcriptional levels, decreased beta-catenin protein, and suppressed the expression of c-Myc, a downstream target gene of Wnt/beta-catenin signaling.	gambogic acid	0-2	catenin beta 1	Homo sapiens	61-73	
34181351-7	2021	GA attenuated beta-catenin transcriptional levels, decreased beta-catenin protein, and suppressed the expression of c-Myc, a downstream target gene of Wnt/beta-catenin signaling.	gambogic acid	0-2	catenin beta 1	Homo sapiens	155-167	
34181351-9	2021	CONCLUSION: Our findings reveal that the molecular mechanism underpinning anti-cancer effect of GA is partially mediated through the inhibition of Wnt/beta-catenin signaling pathway and induction of ER stress induced-apoptosis.	gambogic acid	96-98	catenin beta 1	Homo sapiens	151-163	
32945501-0	2020	Gambogic acid inhibits proliferation and induces apoptosis of human acute T-cell leukemia cells by inducing autophagy and downregulating beta-catenin signaling pathway: Mechanisms underlying the effect of Gambogic acid on T-ALL cells.	gambogic acid	0-13	catenin beta 1	Homo sapiens	137-149	
32945501-0	2020	Gambogic acid inhibits proliferation and induces apoptosis of human acute T-cell leukemia cells by inducing autophagy and downregulating beta-catenin signaling pathway: Mechanisms underlying the effect of Gambogic acid on T-ALL cells.	gambogic acid	205-218	catenin beta 1	Homo sapiens	137-149	
32945501-7	2020	GA inhibited phospho-GSK3beta S9 (p-GSK3beta S9) protein levels to inactivate Wnt signaling and suppress beta-catenin protein levels.	gambogic acid	0-2	catenin beta 1	Homo sapiens	105-117	
32945501-8	2020	In addition, the inhibitory effect of GA on T-ALL was reversed by overexpression of beta-catenin.	gambogic acid	38-40	catenin beta 1	Homo sapiens	84-96	
27669172-0	2016	UNC119 mediates gambogic acid-induced cell-cycle dysregulation through the Gsk3beta/beta-catenin pathway in hepatocellular carcinoma cells.	gambogic acid	16-29	catenin beta 1	Homo sapiens	84-96