PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30181852-0	2018	Drug interactions of meglitinide antidiabetics involving CYP enzymes and OATP1B1 transporter.	meglitinide	21-32	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	57-60	
27722966-13	2005	In contrast, sulphonylureas, meglitinide derivatives and thiazolidinediones are extensively metabolised in the liver via the CYP system and thus, may be subject to drug-drug metabolic interactions.	meglitinide	29-40	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	125-128	
27722966-20	2005	Significantly increased (with CYP inhibitors) or decreased (with CYP inducers) plasma levels of sulphonylureas, meglitinide derivatives and thiazolidinediones have been reported in healthy volunteers, and these pharmacokinetic changes may lead to enhanced or reduced glucose-lowering action, and thus hypoglycaemia or worsening of metabolic control, respectively.	meglitinide	112-123	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	65-68	
15963007-13	2005	In contrast, sulphonylureas, meglitinide derivatives and thiazolidinediones are extensively metabolised in the liver via the CYP system and thus, may be subject to drug-drug metabolic interactions.	meglitinide	29-40	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	125-128	
15963007-21	2005	Significantly increased (with CYP inhibitors) or decreased (with CYP inducers) plasma levels of sulphonylureas, meglitinide derivatives and thiazolidinediones have been reported in healthy volunteers, and these pharmacokinetic changes may lead to enhanced or reduced glucose-lowering action, and thus hypoglycaemia or worsening of metabolic control, respectively.	meglitinide	112-123	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	65-68	
30181852-3	2018	Meglitinides are the substrates of cytochrome P450 (CYP) enzymes and organic anion transporting polypeptide 1B1 (OATP1B1 transporter) and the coadministration of the drugs affecting them will result in pharmacokinetic drug interactions.	meglitinide	0-12	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	35-50	
30181852-3	2018	Meglitinides are the substrates of cytochrome P450 (CYP) enzymes and organic anion transporting polypeptide 1B1 (OATP1B1 transporter) and the coadministration of the drugs affecting them will result in pharmacokinetic drug interactions.	meglitinide	0-12	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	52-55	
30181852-4	2018	This article focuses on the drug interactions of meglitinides involving CYP enzymes and OATP1B1 transporter.	meglitinide	49-61	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	72-75