PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12082016-8 2002 Tp53 was also strongly induced by an N-oxide of quinoline and by dabequine, an experimental antimalarial evaluated in humans; dabequine was reported to be negative in other screens of mutagenicity and clastogenicity but carcinogenic in animal studies. quinoline 48-57 tumor protein p53 Homo sapiens 0-4 20308316-4 2010 We show that the quinoline derivative chloroquine activates the p53 pathway and suppresses growth of glioma cells in vitro and in vivo in an orthotopic (U87MG) human glioblastoma mouse model. quinoline 17-26 tumor protein p53 Homo sapiens 64-67 18645022-6 2008 Quinoline derivative triggered transient, p53-independent G(2)-M arrest in mutant p53 cells (SW620) and succeeding mitotic transition, whereby these cells underwent cell death probably due to aberrant mitosis (mitotic catastrophe). quinoline 0-9 tumor protein p53 Homo sapiens 42-45 18645022-6 2008 Quinoline derivative triggered transient, p53-independent G(2)-M arrest in mutant p53 cells (SW620) and succeeding mitotic transition, whereby these cells underwent cell death probably due to aberrant mitosis (mitotic catastrophe). quinoline 0-9 tumor protein p53 Homo sapiens 82-85