PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23785004-8 2013 Additionally, TNFalpha administration in transgenic mice with cardiac overexpression of Gbetagamma-sequestering peptide betaARK-ct could not prevent betaAR desensitization or cardiac dysfunction showing that GRK2 recruitment to the betaAR is Gbetagamma independent. gbetagamma 88-98 G protein-coupled receptor kinase 2 Mus musculus 208-212 22882301-3 2012 In the crystal structure of the GRK2 paroxetine-Gbetagamma complex, paroxetine binds in the active site of GRK2 and stabilizes the kinase domain in a novel conformation in which a unique regulatory loop forms part of the ligand binding site. gbetagamma 48-58 G protein-coupled receptor kinase 2 Mus musculus 32-36 22882301-3 2012 In the crystal structure of the GRK2 paroxetine-Gbetagamma complex, paroxetine binds in the active site of GRK2 and stabilizes the kinase domain in a novel conformation in which a unique regulatory loop forms part of the ligand binding site. gbetagamma 48-58 G protein-coupled receptor kinase 2 Mus musculus 107-111