PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27013201-4	2016	In previous work, we identified a mutation that specifically abolishes PI3Kbeta binding to Gbetagamma (p110(526KK-DD)).	gbetagamma	91-101	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta	Homo sapiens	71-79	
29046393-5	2017	Whereas CA-Rac1-mediated activation of Akt was blocked in cells expressing a mutated PI3Kbeta that cannot bind Gbetagamma, Gbetagamma and GPCR-mediated activation of Akt was preserved when Rac1 binding to PI3Kbeta was blocked.	gbetagamma	111-121	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta	Homo sapiens	85-93	
29046393-5	2017	Whereas CA-Rac1-mediated activation of Akt was blocked in cells expressing a mutated PI3Kbeta that cannot bind Gbetagamma, Gbetagamma and GPCR-mediated activation of Akt was preserved when Rac1 binding to PI3Kbeta was blocked.	gbetagamma	123-133	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta	Homo sapiens	85-93	
29046393-7	2017	Instead of directly binding to PI3Kbeta, CA-Rac1 acts by enhancing Gbetagamma coupling to PI3Kbeta, as CA-Rac1-mediated Akt activation was blocked by inhibitors of Gbetagamma.	gbetagamma	67-77	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta	Homo sapiens	90-98	
23211529-4	2012	Mutation of this site eliminated Gbetagamma-dependent activation of PI3Kbeta (a dimer of p110beta and the p85 regulatory subunit) in vitro and in cells, without affecting basal activity or phosphotyrosine peptide-mediated activation.	gbetagamma	33-43	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta	Homo sapiens	89-97