PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33831397-6 2021 Mechanistically, HHT and quizartinib cooperatively inhibit FLT3-AKT and its downstream targets GSK3beta, c-Myc, and cyclin D1, cooperatively up-regulate the pro-apoptosis proteins Bim and Bax, and down-regulate the anti-apoptosis protein Mcl1. quizartinib 25-36 MCL1 apoptosis regulator, BCL2 family member Homo sapiens 238-242 29074603-6 2018 Mechanistically, AZD1208 and quizartinib cotreatment decreased expression of the antiapoptotic protein Mcl-1. quizartinib 29-40 MCL1 apoptosis regulator, BCL2 family member Homo sapiens 103-108