PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25344582-8 2015 We found that YM155 induced apoptosis by broad-spectrum inhibition of IAP family member proteins (e.g., CIAP1/2 and FLIP) and induced proapoptotic Bak protein upregulation and activation; the antitumor effect of YM155 treatment with either the DR5 agonist lexatumumab or gemcitabine on pancreatic cancer cells was synergistic. YM 155 14-19 BCL2 antagonist/killer 1 Homo sapiens 147-150