PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23740602-7 2013 TRAIL or YM-155 individually induced minimal killing in highly resistant U373 and LNZ308 cell lines, but combining TRAIL with YM-155 triggered a synergistic proapoptotic response, mediated through mitochondrial dysfunction via activation of caspases-8, -9, -7, -3, poly-ADP-ribose polymerase, and Bid. YM 155 126-132 BH3 interacting domain death agonist Homo sapiens 297-300