PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29689274-8 2018 YM155 induced increases in pro-apoptotic proteins (Bax and Bad), diminished anti-apoptotic proteins (Mcl-1, Bcl-xl, XIAP, survivin) and initiated cleavage of apoptotic marker proteins caspase 3 and PARP. YM 155 0-5 BCL2 associated X, apoptosis regulator Homo sapiens 51-54 28120212-8 2017 In addition, combined treatment with ABT-737 and YM155 induced loss of mitochondrial membrane potential and inhibited interaction of Bcl-xL and Bax. YM 155 49-54 BCL2 associated X, apoptosis regulator Homo sapiens 144-147 27805285-5 2017 Treatment with YM155 increased the release of cytochrome c, smac/DIABLO and apoptosis inducing-factor, and promoted loss of mitochondrial membrane potential, activation of Bax, recruitment of LC3-II to the autophagosomes and apoptosis in Bcl-xL silenced cells. YM 155 15-20 BCL2 associated X, apoptosis regulator Homo sapiens 172-175