PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34692475-17 2021 Conclusions: The preliminary data showed that the combination of anlotinib and anti-PD-1 antibodies demonstrated promising durable antitumor efficacy with acceptable toxicity in patients with various advance tumors, and promoted favorable changes in serum IL-2, IL-4, IL-10, TNF-alpha, IFN-gamma levels and circulating immune cell subsets in clinical responders. anlotinib 65-74 interferon gamma Homo sapiens 286-295 35568074-6 2022 Interestingly, Anlotinib combined with PD-L1 blockade increased the infiltration of IFN-gamma+CD8+ T cells and natural killer (NK) cells, also decreased the quantity of Treg cells and MDSCs in vivo. anlotinib 15-24 interferon gamma Homo sapiens 84-93