PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20393458-3 2010 In the striatum of mice lacking FMRP, we found enhanced activity of diacylglycerol lipase (DAGL), the enzyme limiting 2-arachidonoylglicerol (2-AG) synthesis, associated with altered sensitivity of GABA synapses to the mobilization of this endocannabinoid by mGlu5R stimulation with DHPG. 3,4-dihydroxyphenylglycol 283-287 fragile X messenger ribonucleoprotein 1 Mus musculus 32-36 20393458-5 2010 The effects of FMRP ablation on DAGL activity and on DHPG-mediated inhibition of GABA synapses were enhanced by simultaneous genetic inactivation of FMRP and BC1 RNA. 3,4-dihydroxyphenylglycol 53-57 fragile X messenger ribonucleoprotein 1 Mus musculus 15-19 20393458-5 2010 The effects of FMRP ablation on DAGL activity and on DHPG-mediated inhibition of GABA synapses were enhanced by simultaneous genetic inactivation of FMRP and BC1 RNA. 3,4-dihydroxyphenylglycol 53-57 fragile X messenger ribonucleoprotein 1 Mus musculus 149-153 17298186-4 2007 Stimulation of cortical synaptoneurosomes or primary neuronal cells with the metabotropic glutamate receptor agonist DHPG increased APP translation in wild-type but not fmr-1 knockout samples. 3,4-dihydroxyphenylglycol 117-121 fragile X messenger ribonucleoprotein 1 Mus musculus 169-174