PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34380034-0 2021 Loss of Tsc1 from striatal direct pathway neurons impairs endocannabinoid-LTD and enhances motor routine learning. Endocannabinoids 58-73 TSC complex subunit 1 Mus musculus 8-12 34380034-4 2021 We find that dSPN-specific loss of Tsc1 impairs endocannabinoid-mediated long-term depression (eCB-LTD) at cortico-dSPN synapses and strongly enhances corticostriatal synaptic drive, which is not observed in iSPNs. Endocannabinoids 48-63 TSC complex subunit 1 Mus musculus 35-39