PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29518743-0	2018	Andrographolide suppresses TRIF-dependent signaling of toll-like receptors by targeting TBK1.	andrographolide	0-15	TANK binding kinase 1	Homo sapiens	88-92	
29518743-7	2018	Andrographolide attenuated ligand-independent activation of IRF3 following overexpression of TRIF, TBK1, or IRF3.	andrographolide	0-15	TANK binding kinase 1	Homo sapiens	99-103	
29518743-8	2018	Furthermore, andrographolide inhibited TBK1 kinase activity in vitro.	andrographolide	13-28	TANK binding kinase 1	Homo sapiens	39-43	
29518743-9	2018	These results indicate that andrographolide modulates the TRIF-dependent pathway of TLRs by targeting TBK1 and represents a potential new anti-inflammatory candidate.	andrographolide	28-43	TANK binding kinase 1	Homo sapiens	102-106