PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21682651-0	2012	Andrographolide induces apoptosis in B16F-10 melanoma cells by inhibiting NF-kappaB-mediated bcl-2 activation and modulating p53-induced caspase-3 gene expression.	andrographolide	0-15	caspase 3	Mus musculus	137-146	
21682651-6	2012	The proapoptotic genes p53, Bax, caspase-9, and caspase-3 were found upregulated in andrographolide-treated cells, whereas the antiapoptotic gene bcl-2 was downregulated.	andrographolide	84-99	caspase 3	Mus musculus	48-57	
21682651-8	2012	These results suggest that andrographolide induces apoptosis via inhibiting NF-kappaB-induced bcl-2-mediated survival signaling and modulating p53-induced caspase-3-mediated proapoptotic signaling.	andrographolide	27-42	caspase 3	Mus musculus	155-164