PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27221023-7	2016	The casual relationship analysis indicated that andrographolide (10 and 20mug/ml) appeared to exert the proliferation inhibitory effect through suppression of glutathione peroxidase 1 (GPX1) activity and depleting GSH by promoting its efflux in 3T3-L1 preadipocytes, which subsequently resulted in 2.06-2.41 fold increase in ROS accumulation.	andrographolide	48-63	glutathione peroxidase 1	Homo sapiens	159-183	
27221023-7	2016	The casual relationship analysis indicated that andrographolide (10 and 20mug/ml) appeared to exert the proliferation inhibitory effect through suppression of glutathione peroxidase 1 (GPX1) activity and depleting GSH by promoting its efflux in 3T3-L1 preadipocytes, which subsequently resulted in 2.06-2.41 fold increase in ROS accumulation.	andrographolide	48-63	glutathione peroxidase 1	Homo sapiens	185-189	
27221023-9	2016	SIGNIFICANCE: Taken together, our study reveals that suppression of GPX1 and GSH depletion by andrographolide seems to play a critical role in the inhibition of 3T3-L1 preadipocytes proliferation, which might have implication for obesity prevention and treatment.	andrographolide	94-109	glutathione peroxidase 1	Homo sapiens	68-72