PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34300281-0	2021	Decreased Production of TNF-alpha and IL-6 Inflammatory Cytokines in Non-Pregnant Idiopathic RPL Women Immunomodulatory Effect of Sildenafil Citrate on the Cellular Response of Idiopathic RPL Women.	Sildenafil Citrate	130-148	tumor necrosis factor	Homo sapiens	24-33	
26376530-0	2015	Effects of sildenafil citrate and etanercept treatment on TNF-alpha levels in peripheral blood of women with recurrent miscarriage.	Sildenafil Citrate	11-29	tumor necrosis factor	Homo sapiens	58-67	
26376530-1	2015	OBJECTIVES: The aim of the study was to determine serum concentrations of a proinflammatory cytokine, tumor necrosis factor-alpha (TNF-alpha), in patients with recurrent abortions undergoing treatment with sildenafil or etanercept.	Sildenafil Citrate	206-216	tumor necrosis factor	Homo sapiens	102-129	
26376530-1	2015	OBJECTIVES: The aim of the study was to determine serum concentrations of a proinflammatory cytokine, tumor necrosis factor-alpha (TNF-alpha), in patients with recurrent abortions undergoing treatment with sildenafil or etanercept.	Sildenafil Citrate	206-216	tumor necrosis factor	Homo sapiens	131-140	
26376530-7	2015	Moreover we found a tendency for the concentration of TNF-alpha to increase in sera of patients treated with sildenafil after therapy completion (19 +- 29 vs. 15.4 +- 26.7 pg/ml).	Sildenafil Citrate	109-119	tumor necrosis factor	Homo sapiens	54-63	
25577741-8	2015	Likewise, TNF-alpha was acutely decreased after sildenafil (maximal response of -13pg/ml, 2h).	Sildenafil Citrate	48-58	tumor necrosis factor	Homo sapiens	10-19	
21220057-2	2011	The present study showed that sildenafil, a PDE5 inhibitor, significantly suppressed NO, interleukin 1beta (IL-1beta) and tumor necrosis factor alpha (TNF-alpha) production induced by LPS in microglial cells through decreasing the protein and/or mRNA expressions of inducible NO synthase (iNOS), IL-1beta and TNF-alpha in a concentration-dependent manner.	Sildenafil Citrate	30-40	tumor necrosis factor	Homo sapiens	122-149	
21220057-2	2011	The present study showed that sildenafil, a PDE5 inhibitor, significantly suppressed NO, interleukin 1beta (IL-1beta) and tumor necrosis factor alpha (TNF-alpha) production induced by LPS in microglial cells through decreasing the protein and/or mRNA expressions of inducible NO synthase (iNOS), IL-1beta and TNF-alpha in a concentration-dependent manner.	Sildenafil Citrate	30-40	tumor necrosis factor	Homo sapiens	151-160	
21220057-2	2011	The present study showed that sildenafil, a PDE5 inhibitor, significantly suppressed NO, interleukin 1beta (IL-1beta) and tumor necrosis factor alpha (TNF-alpha) production induced by LPS in microglial cells through decreasing the protein and/or mRNA expressions of inducible NO synthase (iNOS), IL-1beta and TNF-alpha in a concentration-dependent manner.	Sildenafil Citrate	30-40	tumor necrosis factor	Homo sapiens	309-318	
19185976-11	2010	Tadalafil in combination with Mox-LDL and TNF-alpha showed a decrease of IL-8 (p<0.05) compared with sildenafil and vardenafil.	Sildenafil Citrate	104-114	tumor necrosis factor	Homo sapiens	42-51