PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26887051-7	2016	AR-12 combined with sildenafil in a GRP78 plus HSP27 -dependent fashion to profoundly activate an eIF2alpha/ATF4/CHOP/Beclin1 pathway in parallel with inactivating mTOR and increasing ATG13 phosphorylation, collectively resulting in formation of punctate toxic autophagosomes.	Sildenafil Citrate	20-30	heat shock protein family A (Hsp70) member 5	Homo sapiens	36-41	
27903966-4	2017	[Pemetrexed + sildenafil] reduced the expression of c-FLIP-s, MCL-1 and BCL-XL that was blocked in a cell-type -dependent fashion by either over-expression of HSP90 / GRP78 / HSP70 / HSP27 or by blockade of eIF2alpha-CHOP signaling.	Sildenafil Citrate	14-24	heat shock protein family A (Hsp70) member 5	Homo sapiens	167-172	
25858032-2	2015	Sorafenib/regorafenib and the multi-kinase inhibitor pazopanib (Votrient) interacted with sildenafil (Viagra) to further rapidly reduce GRP78 levels in eukaryotes and as single agents to reduce Dna K levels in prokaryotes.	Sildenafil Citrate	90-100	heat shock protein family A (Hsp70) member 5	Homo sapiens	136-141	
25858032-2	2015	Sorafenib/regorafenib and the multi-kinase inhibitor pazopanib (Votrient) interacted with sildenafil (Viagra) to further rapidly reduce GRP78 levels in eukaryotes and as single agents to reduce Dna K levels in prokaryotes.	Sildenafil Citrate	102-108	heat shock protein family A (Hsp70) member 5	Homo sapiens	136-141	
25546329-2	2015	The GRP78 inhibitor OSU-03012 (AR-12) interacted with sildenafil (Viagra) or tadalafil (Cialis) to rapidly reduce GRP78 levels in eukaryotes and as a single agent reduce Dna K levels in prokaryotes.	Sildenafil Citrate	54-64	heat shock protein family A (Hsp70) member 5	Homo sapiens	4-9	
25546329-2	2015	The GRP78 inhibitor OSU-03012 (AR-12) interacted with sildenafil (Viagra) or tadalafil (Cialis) to rapidly reduce GRP78 levels in eukaryotes and as a single agent reduce Dna K levels in prokaryotes.	Sildenafil Citrate	54-64	heat shock protein family A (Hsp70) member 5	Homo sapiens	114-119	
25546329-2	2015	The GRP78 inhibitor OSU-03012 (AR-12) interacted with sildenafil (Viagra) or tadalafil (Cialis) to rapidly reduce GRP78 levels in eukaryotes and as a single agent reduce Dna K levels in prokaryotes.	Sildenafil Citrate	66-72	heat shock protein family A (Hsp70) member 5	Homo sapiens	4-9	
25546329-2	2015	The GRP78 inhibitor OSU-03012 (AR-12) interacted with sildenafil (Viagra) or tadalafil (Cialis) to rapidly reduce GRP78 levels in eukaryotes and as a single agent reduce Dna K levels in prokaryotes.	Sildenafil Citrate	66-72	heat shock protein family A (Hsp70) member 5	Homo sapiens	114-119	
25736380-3	2015	Treatment of cells with OSU-03012/sildenafil: abolished the expression of multiple oncogenic growth factor receptors and plasma membrane drug efflux pumps and caused a rapid degradation of GRP78 and other HSP70 and HSP90 family chaperone proteins.	Sildenafil Citrate	34-44	heat shock protein family A (Hsp70) member 5	Homo sapiens	189-194