PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25108355-0	2014	Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs.	Lenalidomide	37-49	damage specific DNA binding protein 1	Homo sapiens	32-36	
28087699-4	2017	Pharmacological inhibition or genetic ablation of the Abl-DDB1-DDA1 axis decreases the ubiquitination of CRL4 substrates, including IKZF1 and IKZF3, in lenalidomide-treated multiple myeloma cells.	Lenalidomide	152-164	damage specific DNA binding protein 1	Homo sapiens	58-62	
30234487-1	2018	The cereblon modulating agents (CMs) including lenalidomide, pomalidomide and CC-220 repurpose the Cul4-RBX1-DDB1-CRBN (CRL4CRBN) E3 ubiquitin ligase complex to induce the degradation of specific neomorphic substrates via polyubiquitination in conjunction with E2 ubiquitin-conjugating enzymes, which have until now remained elusive.	Lenalidomide	47-59	damage specific DNA binding protein 1	Homo sapiens	109-113	
25108355-1	2014	The Cul4-Rbx1-DDB1-Cereblon E3 ubiquitin ligase complex is the target of thalidomide, lenalidomide and pomalidomide, therapeutically important drugs for multiple myeloma and other B-cell malignancies.	Lenalidomide	86-98	damage specific DNA binding protein 1	Homo sapiens	14-18	
25043012-4	2014	Here we present crystal structures of the DDB1-CRBN complex bound to thalidomide, lenalidomide and pomalidomide.	Lenalidomide	82-94	damage specific DNA binding protein 1	Homo sapiens	42-46	
22552008-3	2012	Our studies demonstrate that thalidomide, lenalidomide and another immunomodulatory drug, pomalidomide, bound endogenous CRBN and recombinant CRBN-DNA damage binding protein-1 (DDB1) complexes.	Lenalidomide	42-54	damage specific DNA binding protein 1	Homo sapiens	142-175	
22552008-3	2012	Our studies demonstrate that thalidomide, lenalidomide and another immunomodulatory drug, pomalidomide, bound endogenous CRBN and recombinant CRBN-DNA damage binding protein-1 (DDB1) complexes.	Lenalidomide	42-54	damage specific DNA binding protein 1	Homo sapiens	177-181