PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33273169-7 2020 Agents such as the Bruton tyrosine kinase (BTK) inhibitor ibrutinib or immunomodulatory drugs such as lenalidomide and pomalidomide have shown promising response rates in the relapsed setting. Lenalidomide 102-114 Bruton tyrosine kinase Homo sapiens 43-46 25984532-6 2015 Future efforts should aim at targeting the role of NF-kappaB resistance in clinical trials, where novel agents like lenalidomide and proteasome inhibitors with established activity in this perspective will be an important component in combination therapy, along with new monoclonal antibody, BTK-inhibitors, and other novel therapy agents. Lenalidomide 116-128 Bruton tyrosine kinase Homo sapiens 292-295 30423172-3 2019 Agents like the Bruton tyrosine kinase (BTK) inhibitor ibrutinib or immunomodulatory drugs (IMiDs) like pomalidomide and lenalidomide have shown promising high response rates in the salvage setting. Lenalidomide 121-133 Bruton tyrosine kinase Homo sapiens 16-38 30423172-3 2019 Agents like the Bruton tyrosine kinase (BTK) inhibitor ibrutinib or immunomodulatory drugs (IMiDs) like pomalidomide and lenalidomide have shown promising high response rates in the salvage setting. Lenalidomide 121-133 Bruton tyrosine kinase Homo sapiens 40-43 22698399-5 2012 Blockade of B cell receptor signaling using the BTK inhibitor ibrutinib also downregulates IRF4 and consequently synergizes with lenalidomide in killing ABC DLBCLs, suggesting attractive therapeutic strategies. Lenalidomide 129-141 Bruton tyrosine kinase Homo sapiens 48-51 22975686-0 2013 BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-kappaB. Lenalidomide 85-97 Bruton tyrosine kinase Homo sapiens 0-3