PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22525275-0 2013 Lenalidomide promotes p53 degradation by inhibiting MDM2 auto-ubiquitination in myelodysplastic syndrome with chromosome 5q deletion. Lenalidomide 0-12 MDM2 proto-oncogene Homo sapiens 52-56 22525275-4 2013 More importantly, we show that lenalidomide (Len) acts to stabilize MDM2, thereby accelerating p53 degradation. Lenalidomide 31-43 MDM2 proto-oncogene Homo sapiens 68-72 22525275-4 2013 More importantly, we show that lenalidomide (Len) acts to stabilize MDM2, thereby accelerating p53 degradation. Lenalidomide 45-48 MDM2 proto-oncogene Homo sapiens 68-72 25295231-11 2014 Through its inhibitory effect on PP2A, lenalidomide stabilizes MDM2 to restore p53 degradation in erythroid precursors, with subsequent arrest in G2/M. Lenalidomide 39-51 MDM2 proto-oncogene Homo sapiens 63-67