PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30707764-0 2019 Phase 1 study of lenalidomide plus dose-adjusted EPOCH-R in patients with aggressive B-cell lymphomas with deregulated MYC and BCL2. Lenalidomide 17-29 BCL2 apoptosis regulator Homo sapiens 127-131 23012246-7 2012 RSK2(Ser227) inhibition resulting from BI-D1870 treatment restored lenalidomide-induced direct cytotoxicity of myeloma cells from interleukin-6-mediated cell protection, showed no cross-resistance to bortezomib, and exerted additive/synergistic antiproliferative effects in conjunction with the mTOR, histone deacetylase, and BH3-mimicking BCL2/BCLX(L) inhibitors. Lenalidomide 67-79 BCL2 apoptosis regulator Homo sapiens 340-344 24236538-7 2014 This cytotoxic effect and BCL2 downregulation were further potentiated when AT-101 was combined with lenalidomide/dexamethasone (LDA). Lenalidomide 101-113 BCL2 apoptosis regulator Homo sapiens 26-30 22109882-0 2012 The immunomodulatory drug lenalidomide restores a vitamin D sensitive phenotype to the vitamin D resistant breast cancer cell line MDA-MB-231 through inhibition of BCL-2: potential for breast cancer therapeutics. Lenalidomide 26-38 BCL2 apoptosis regulator Homo sapiens 164-169 22171982-0 2012 Downregulation of BCL2 by AT-101 enhances the antileukaemic effect of lenalidomide both by an immune dependant and independent manner. Lenalidomide 70-82 BCL2 apoptosis regulator Homo sapiens 18-22 22109882-10 2012 An apoptosis protein array showed that the 1,25-D3 and lenalidomide combination increased pro-apoptotic proteins (phosphorylated p53) and decreased BCL-2 expression. Lenalidomide 55-67 BCL2 apoptosis regulator Homo sapiens 148-153