PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35293663-0	2022	OSI-027 inhibits the tumorigenesis of colon cancer through mediation of c-Myc/FOXO3a/PUMA axis.	OSI 027	0-7	BCL2 binding component 3	Homo sapiens	85-89	
35293663-7	2022	In addition, OSI-027 induced the apoptosis of colon cancer cells via upregulation of PUMA.	OSI 027	13-20	BCL2 binding component 3	Homo sapiens	85-89	
35293663-8	2022	OSI-027 promoted the expression of PUMA by activation of FOXO3a, and c-Myc knockdown partially increased FOXO3a and PUMA level.	OSI 027	0-7	BCL2 binding component 3	Homo sapiens	35-39