PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26983803-7 2016 Tanshinone IIA also increased CHOP and activated the PERK-ATF4 pathway suggesting that tanshinone IIA increased DR5 and CHOP by activating the PERK-ATF4 pathway. tanshinone 87-97 DNA damage inducible transcript 3 Homo sapiens 30-34 28212571-6 2017 Notably, Tan I upregulated CCAAT-enhancer-binding protein homologous protein (CHOP), inositol-requiring protein-1 (IRE1) and p-c-Jun N-terminal kinase (p-JNK), but silencing of IRE1 or p62 and JNK inhibitor SP600125 blocked the LC3II accumulation in Tan I-treated H28 cells. tanshinone 9-14 DNA damage inducible transcript 3 Homo sapiens 27-76 28212571-6 2017 Notably, Tan I upregulated CCAAT-enhancer-binding protein homologous protein (CHOP), inositol-requiring protein-1 (IRE1) and p-c-Jun N-terminal kinase (p-JNK), but silencing of IRE1 or p62 and JNK inhibitor SP600125 blocked the LC3II accumulation in Tan I-treated H28 cells. tanshinone 9-14 DNA damage inducible transcript 3 Homo sapiens 78-82 26983803-7 2016 Tanshinone IIA also increased CHOP and activated the PERK-ATF4 pathway suggesting that tanshinone IIA increased DR5 and CHOP by activating the PERK-ATF4 pathway. tanshinone 87-97 DNA damage inducible transcript 3 Homo sapiens 120-124 26996008-7 2016 Compared with the control group, tanshinone IIA could apparently induce apoptosis of Ec-109 cells, and the level of Caspase-4 and CHOP (p < 0.01) obviously increased. tanshinone 33-47 DNA damage inducible transcript 3 Homo sapiens 130-134