PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29589392-6	2018	Pioglitazone remarkably reduced the expression of ATF6alpha, GRP78, and monocyte chemoattractant protein-1, prevented alpha-cell infiltration into the pancreatic islets, and upregulated glucose transporter 2 (Glut2) expression in beta-cells.	Pioglitazone	0-12	chemokine (C-C motif) ligand 2	Mus musculus	72-106	
31263138-5	2019	Here we show that treatment with PPARgamma agonists (rosiglitazone or pioglitazone) in primary cultures of mouse glial cells reversed EcoHIV-induced inflammatory genes (TNFalpha, IL-1beta, CCL2, CCL3, CXCL10) and indicator of oxidative stress (iNOS).	Pioglitazone	70-82	chemokine (C-C motif) ligand 2	Mus musculus	189-193	
29222347-6	2018	Treatment with pioglitazone reduced the density of CLS in periprostatic fat and suppressed levels of TNFalpha, TGFbeta, and the chemokine monocyte chemoattractant protein-1 (MCP-1).	Pioglitazone	15-27	chemokine (C-C motif) ligand 2	Mus musculus	174-179	
29222347-7	2018	Importantly, the ability of pioglitazone to suppress periprostatic WAT inflammation was abrogated in MCP-1 knockout mice.	Pioglitazone	28-40	chemokine (C-C motif) ligand 2	Mus musculus	101-106	
29222347-9	2018	Pioglitazone blocked TNFalpha-mediated induction of MCP-1 in 3T3-L1 cells, an effect that was attenuated when either adiponectin or AdipoR2 were silenced.	Pioglitazone	0-12	chemokine (C-C motif) ligand 2	Mus musculus	52-57	
29222347-10	2018	Taken together, pioglitazone-mediated induction of adiponectin suppressed the elevation in MCP-1 levels, thereby attenuating obesity-related periprostatic WAT inflammation.	Pioglitazone	16-28	chemokine (C-C motif) ligand 2	Mus musculus	91-96	
28458349-10	2017	Expression of IL-6 and MCP-1 stimulated by CLP was reduced by pioglitazone treatment.	Pioglitazone	62-74	chemokine (C-C motif) ligand 2	Mus musculus	23-28	
27530729-8	2017	Pioglitazone dose-dependently decreased Tnf, Il6, Ccl2, Ptgs2, and Socs3 expression in WAT, in association with upregulation of Lpl, Ap2, Slc2a4, and Adipoq expression, indicating improvement in endotoxin-induced IR.	Pioglitazone	0-12	chemokine (C-C motif) ligand 2	Mus musculus	50-54	
18212290-9	2008	Treatment of transplanted ApoE(-/-) mice with pioglitazone decreased macrophage content of the transplanted visceral fat pad and reduced plasma monocyte chemoattractant protein-1.	Pioglitazone	46-58	chemokine (C-C motif) ligand 2	Mus musculus	144-178	
21962804-10	2011	Treatment with pioglitazone significantly inhibited the increases in the serum interleukin-6 and monocyte chemoattractant protein-1 (MCP-1) levels after CLP and lowered the mRNA expressions of proinflammatory cytokines, interleukin-6, and MCP-1 in omental tissue after CLP.	Pioglitazone	15-27	chemokine (C-C motif) ligand 2	Mus musculus	97-131	
21962804-10	2011	Treatment with pioglitazone significantly inhibited the increases in the serum interleukin-6 and monocyte chemoattractant protein-1 (MCP-1) levels after CLP and lowered the mRNA expressions of proinflammatory cytokines, interleukin-6, and MCP-1 in omental tissue after CLP.	Pioglitazone	15-27	chemokine (C-C motif) ligand 2	Mus musculus	133-138	
21962804-10	2011	Treatment with pioglitazone significantly inhibited the increases in the serum interleukin-6 and monocyte chemoattractant protein-1 (MCP-1) levels after CLP and lowered the mRNA expressions of proinflammatory cytokines, interleukin-6, and MCP-1 in omental tissue after CLP.	Pioglitazone	15-27	chemokine (C-C motif) ligand 2	Mus musculus	239-244	
19690061-5	2009	Not only the numbers of M1 ATMs and the expression of M1 marker genes, such as tumor necrosis factor-alpha and monocyte chemoattractant protein-1, but also the M1-to-M2 ratio were increased by an HFD and decreased by subsequent pioglitazone treatment, suggesting the correlation with whole-body insulin sensitivity.	Pioglitazone	228-240	chemokine (C-C motif) ligand 2	Mus musculus	111-145	
16735678-7	2006	Treatment with pioglitazone significantly suppressed graft expression of interferon-gamma and monocyte chemoattractant protein-1.	Pioglitazone	15-27	chemokine (C-C motif) ligand 2	Mus musculus	94-128	
16735678-9	2006	Pioglitazone-treated allografts showed significantly reduced expression of interferon-gamma, interleukin-10, and monocyte chemoattractant protein-1.	Pioglitazone	0-12	chemokine (C-C motif) ligand 2	Mus musculus	113-147	
12473562-8	2002	Improvement of LV function by pioglitazone was accompanied by a decrease in myocyte hypertrophy and interstitial fibrosis and a reduced expression of tumor necrosis factor-alpha, transforming growth factor-beta, and monocyte chemoattractant protein-1 genes in the noninfarcted LV from MI mice.	Pioglitazone	30-42	chemokine (C-C motif) ligand 2	Mus musculus	216-250