PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19281808-0	2009	Involvement of glucocorticoid receptor and peroxisome proliferator activated receptor-gamma in pioglitazone mediated chronic gastric ulcer healing in rats.	Pioglitazone	95-107	nuclear receptor subfamily 3, group C, member 1	Rattus norvegicus	15-38	
19281808-5	2009	Moreover, it significantly upregulated protein levels of glucocorticoid receptor demonstrating its possible involvement in pioglitazone mediated ulcer healing along with PPAR-gamma.	Pioglitazone	123-135	nuclear receptor subfamily 3, group C, member 1	Rattus norvegicus	57-80	
19281808-7	2009	Moreover, pharmacological inhibition of glucocorticoid receptor function by its antagonist (RU486) inhibited pioglitazone mediated downregulation of TNF-alpha and IL-1beta gene expression confirming involvement of glucocorticoid receptor in pioglitazone mediated ulcer healing.	Pioglitazone	109-121	nuclear receptor subfamily 3, group C, member 1	Rattus norvegicus	40-63	
19281808-7	2009	Moreover, pharmacological inhibition of glucocorticoid receptor function by its antagonist (RU486) inhibited pioglitazone mediated downregulation of TNF-alpha and IL-1beta gene expression confirming involvement of glucocorticoid receptor in pioglitazone mediated ulcer healing.	Pioglitazone	109-121	nuclear receptor subfamily 3, group C, member 1	Rattus norvegicus	214-237	
19281808-7	2009	Moreover, pharmacological inhibition of glucocorticoid receptor function by its antagonist (RU486) inhibited pioglitazone mediated downregulation of TNF-alpha and IL-1beta gene expression confirming involvement of glucocorticoid receptor in pioglitazone mediated ulcer healing.	Pioglitazone	241-253	nuclear receptor subfamily 3, group C, member 1	Rattus norvegicus	40-63	
19281808-8	2009	Co-immunoprecipitation studies further established association of PPAR-gamma with glucocorticoid receptor during ulcer healing which was enhanced following pioglitazone administration.	Pioglitazone	156-168	nuclear receptor subfamily 3, group C, member 1	Rattus norvegicus	82-105	
26084260-8	2015	In vitro incubation of MAT obtained from overfed rats demonstrated that pioglitazone induced a down-regulation of GR gene expression and normalized glucocorticoid-induced stimulation of 11beta-HSD1 and plasminogen-activator inhibitor type 1 mRNAs.	Pioglitazone	72-84	nuclear receptor subfamily 3, group C, member 1	Rattus norvegicus	114-116	
26084260-10	2015	They demonstrate that pioglitazone, in addition to its well-established effect on adipose tissue redistribution and adiponectin secretion, reverses programing-induced adipose GR, 11beta-HSD1, and proinflammatory cytokines overexpression, possibly through a GR-dependent mechanism.	Pioglitazone	22-34	nuclear receptor subfamily 3, group C, member 1	Rattus norvegicus	175-177	
26084260-10	2015	They demonstrate that pioglitazone, in addition to its well-established effect on adipose tissue redistribution and adiponectin secretion, reverses programing-induced adipose GR, 11beta-HSD1, and proinflammatory cytokines overexpression, possibly through a GR-dependent mechanism.	Pioglitazone	22-34	nuclear receptor subfamily 3, group C, member 1	Rattus norvegicus	257-259	
21352843-3	2011	Using primary cultures of VSMC derived from rat aorta, we showed that pioglitazone significantly increases 11HSD1 activity and mRNA expression in a dose-dependent manner with EC(50) 243 nM and that this effect is not blocked by RU 486, an antagonist of the glucocorticoid receptor.	Pioglitazone	70-82	nuclear receptor subfamily 3, group C, member 1	Rattus norvegicus	257-280