PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25450818-0 2015 Comparative effects of metformin and pioglitazone on fetuin-A and osteoprotegerin concentrations in patients with newly diagnosed diabetes: A randomized clinical trial. Pioglitazone 37-49 alpha 2-HS glycoprotein Homo sapiens 53-61 18702951-0 2008 Effects of pioglitazone on serum fetuin-A levels in patients with type 2 diabetes mellitus. Pioglitazone 11-23 alpha 2-HS glycoprotein Homo sapiens 33-41 18702951-6 2008 To address this, we investigated the effects of representative insulin-sensitizing therapies such as pioglitazone, metformin, and aerobic exercise on fetuin-A levels. Pioglitazone 101-113 alpha 2-HS glycoprotein Homo sapiens 150-158 18702951-13 2008 We hypothesize that pioglitazone could partially ameliorate insulin resistance via modulating fetuin-A levels. Pioglitazone 20-32 alpha 2-HS glycoprotein Homo sapiens 94-102 34185201-5 2021 The other major area of exploration in the present review is based on the new targets for the modulation of fetuin-A, like calorie restriction and novel pharmacological agents, such as rosuvastatin, metformin, and pioglitazone which are successfully implicated in the management of various liver-related complications. Pioglitazone 214-226 alpha 2-HS glycoprotein Homo sapiens 108-116 32113823-8 2020 In the pioglitazone group, fetuin-A levels also decreased after 24 weeks (659.3+-111.8 vs. 538.1+- 101.0mug/mL, P<0.05) but not to the level of the liraglutide group. Pioglitazone 7-19 alpha 2-HS glycoprotein Homo sapiens 27-35 30123261-0 2018 Low-Dose Spironolactone-Pioglitazone-Metformin Normalizes Circulating Fetuin-A Concentrations in Adolescent Girls with Polycystic Ovary Syndrome. Pioglitazone 24-36 alpha 2-HS glycoprotein Homo sapiens 70-78 25450818-7 2015 Pioglitazone resulted in a significant reduction in both fetuin-A and OPG in men, but only fetuin-A in women. Pioglitazone 0-12 alpha 2-HS glycoprotein Homo sapiens 57-65 25450818-10 2015 In men, pioglitazone more effectively decreased fetuin-A levels in both uni- (p=0.011) and multivariate models (p=0.015) and OPG levels in only uni- (p=0.023) but not the multivariate model (p=0.547). Pioglitazone 8-20 alpha 2-HS glycoprotein Homo sapiens 48-56 25450818-11 2015 CONCLUSIONS: Metformin and pioglitazone differentially affect fetuin-A and osteoprotegrin levels in diabetic women and men. Pioglitazone 27-39 alpha 2-HS glycoprotein Homo sapiens 62-70 26105582-8 2015 Fenofibrate, alone and in combination with pioglitazone, significantly decreased triacylglycerol, hs-CRP, IL-6, fetuin A and increased sirtuin 1 levels (P<0.001) which suggests that it can be used to delay the complications of obesity and T2DM. Pioglitazone 43-55 alpha 2-HS glycoprotein Homo sapiens 112-120 24551137-7 2014 In addition, GW 9662, an inhibitor of peroxisome proliferator-activated receptor (PPAR) gamma, reversed pioglitazone-induced suppression of fetuin-A, suggesting that thiazolidinedione derivatives may have common characteristics with regard to fetuin-A suppression, possibly through PPARgammaactivation. Pioglitazone 104-116 alpha 2-HS glycoprotein Homo sapiens 140-148 24551137-7 2014 In addition, GW 9662, an inhibitor of peroxisome proliferator-activated receptor (PPAR) gamma, reversed pioglitazone-induced suppression of fetuin-A, suggesting that thiazolidinedione derivatives may have common characteristics with regard to fetuin-A suppression, possibly through PPARgammaactivation. Pioglitazone 104-116 alpha 2-HS glycoprotein Homo sapiens 243-251 24551137-9 2014 These findings suggest that pioglitazone may partially ameliorate insulin resistance through its direct inhibitory effects on fetuin-A expression in the liver. Pioglitazone 28-40 alpha 2-HS glycoprotein Homo sapiens 126-134 25468829-5 2015 Weight loss, aerobic exercise, metformin and pioglitazone have each been shown to be effective for reducing FetA level. Pioglitazone 45-57 alpha 2-HS glycoprotein Homo sapiens 108-112 24551137-0 2014 Direct inhibitory effects of pioglitazone on hepatic fetuin-A expression. Pioglitazone 29-41 alpha 2-HS glycoprotein Homo sapiens 53-61 24551137-3 2014 We previously reported that pioglitazone treatment significantly reduced serum fetuin-A levels in patients with type 2 diabetes. Pioglitazone 28-40 alpha 2-HS glycoprotein Homo sapiens 79-87