PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27548145-4 2016 Pioglitazone treatment significantly inhibited various effector T cell differentiations including Th1, Th2, and Th17 cells from female naive T cells, but it selectively reduced IL-17 production in male Th17 differentiation. Pioglitazone 0-12 negative elongation factor complex member C/D, Th1l Mus musculus 98-101 27548145-5 2016 Interestingly, pioglitazone and estradiol (E2) co-treatment of T cells in males inhibited differentiation of Th1, Th2, and Th17 cells, suggesting a mechanism for the greater sensitivity of PPARgamma to ligand treatment in the regulation of effector T cell differentiation in females. Pioglitazone 15-27 negative elongation factor complex member C/D, Th1l Mus musculus 109-112