PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27446311-7 2016 In conclusion, RBP4 may be an effective predictor for diabetic atherosclerosis; pioglitazone is able to decrease RBP4 and NF-kappaB, which may partly contribute to its protective effect against diabetic atherosclerosis. Pioglitazone 80-92 retinol binding protein 4 Rattus norvegicus 113-117 25634757-0 2015 Pioglitazone lowers serum retinol binding protein 4 by suppressing its expression in adipose tissue of obese rats. Pioglitazone 0-12 retinol binding protein 4 Rattus norvegicus 26-51 25634757-3 2015 We investigated whether, and how, pioglitazone modulates serum level of retinol binding protein 4 (RBP4), an adipocytokine associated with obesity and insulin resistance. Pioglitazone 34-46 retinol binding protein 4 Rattus norvegicus 72-97 25634757-3 2015 We investigated whether, and how, pioglitazone modulates serum level of retinol binding protein 4 (RBP4), an adipocytokine associated with obesity and insulin resistance. Pioglitazone 34-46 retinol binding protein 4 Rattus norvegicus 99-103 25634757-5 2015 RESULTS: Pioglitazone treatment significantly decreased serum RBP4 levels in obese rats, which was correlated with reduced body weight and increased insulin sensitivity. Pioglitazone 9-21 retinol binding protein 4 Rattus norvegicus 62-66 25634757-6 2015 Moreover, pioglitazone greatly decreased RBP4 mRNA and protein levels in adipose tissue but not in the liver. Pioglitazone 10-22 retinol binding protein 4 Rattus norvegicus 41-45 25634757-8 2015 CONCLUSION: These results demonstrate that pioglitazone inhibits the level of serum RPB4 by suppressing RBP4 expression in adipose tissue of obese rats, suggesting that inhibiting RBP4 expression in adipocytes may provide a mechanism by which pioglitazone improves insulin sensitivity in insulin-resistant subjects. Pioglitazone 43-55 retinol binding protein 4 Rattus norvegicus 104-108 25634757-8 2015 CONCLUSION: These results demonstrate that pioglitazone inhibits the level of serum RPB4 by suppressing RBP4 expression in adipose tissue of obese rats, suggesting that inhibiting RBP4 expression in adipocytes may provide a mechanism by which pioglitazone improves insulin sensitivity in insulin-resistant subjects. Pioglitazone 43-55 retinol binding protein 4 Rattus norvegicus 180-184