PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28810524-11 2017 Pioglitazone treatment significantly increased urinary calcium, serum TRAP, mRNA expression of RANKL, PPAR-gamma as well as significantly decreased Runx2, OPG, osteocalcin and AMPK levels in diabetic rats. Pioglitazone 0-12 TNF receptor superfamily member 11B Rattus norvegicus 155-158 23982996-10 2013 Pioglitazone reduced the ratio of RANKL to OPG, in both the serum and the inflamed synovium. Pioglitazone 0-12 TNF receptor superfamily member 11B Rattus norvegicus 43-46 23982996-13 2013 CONCLUSION: Pioglitazone decreased the level of inflammatory bone destruction and protected the bone microarchitecture in rats with AIA by controlling the circulating and local expression of IL-17, with a subsequent decrease in the RANKL-to-OPG ratio. Pioglitazone 12-24 TNF receptor superfamily member 11B Rattus norvegicus 241-244