PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35510808-13 2022 PXL065 was confirmed to lack PPARgamma agonism but retained ACSL4 activity of pioglitazone. Pioglitazone 78-90 acyl-CoA synthetase long chain family member 4 Homo sapiens 60-65 35038927-6 2022 Most importantly, ferroptosis inhibitors, including two FDA-approved drugs, rosiglitazone (ROSI; ACSL4 inhibitor) and pioglitazone (PIO; ACSL4 inhibitor), decreased the viral load of human enteroviruses and coronaviruses, suggesting that ACSL4 is a target for counteracting viral infection. Pioglitazone 118-130 acyl-CoA synthetase long chain family member 4 Homo sapiens 137-142 35038927-6 2022 Most importantly, ferroptosis inhibitors, including two FDA-approved drugs, rosiglitazone (ROSI; ACSL4 inhibitor) and pioglitazone (PIO; ACSL4 inhibitor), decreased the viral load of human enteroviruses and coronaviruses, suggesting that ACSL4 is a target for counteracting viral infection. Pioglitazone 118-130 acyl-CoA synthetase long chain family member 4 Homo sapiens 238-243